is helping to establish and optimize the use of a fully integrated set of multipurpose capabilities. A science-based approach INL has led a fundamental shift in how nuclear energy research and development is approached at universities national labs and within regulatory and policy organizations. These efforts are transforming the way DOE-NE executes its nuclear research portfolio through the integration of fundamental research modeling and simulation small-scale experimentation and larger scale demonstrations that are closely coordinated with industrial and international partners. This approach can make engineering-scale irradiation and testing far more focused and efficient. It may also eliminate some costly prototype demonstrations. Light-water reactor modeling The Consortium for Advanced Simulation of Light Water Reactors CASL one of the DOEs Energy Innovation Hubs is developing a set of predictive models 3 that simulate a light water reactor power plant. These simulations will help improve operating efficiencies extend operating lifetimes and reduce operating costs and waste volumes. The partnership which includes several DOE laboratories leading universities and industries selected the INL- developed MOOSEBISONMARMOT modeling and simulation code suite as the basis for its fuels performance application read more on page 21. INL is expanding the use of science-based nuclear energy research a complex undertaking that has direct applications for developing advanced fuels that can be used in light water reactors.